Bioinformatic Analysis of the Association Between Myocardial Disease and Diesel Particulate Matter

The etiological connection between Diesel Particulate Matter (DPM) and heart failure is unclear, despite the fact that multiple experimental studies have found a strong correlation DPM failure. We investigated myocardial infarction using biological big data. Distinct gene expression profiles related to were obtained from open-access genome databases, network analysis software was used investigate their interaction. detrimental effects of on cardiac cells understand association them. putative signaling networks 33 genes with differential identified studied. In addition increasing prediction accuracy, our study validation literature-based enhance knowledge mechanisms underlying DPM-related disease.